Téma: 

Epidemiology of gastric cancer

Ivan Pleško

Despite gradually decreasing mortality and incidence rates observed from 1930 in developed and later also in other countries of the world stomach cancer is in the year 2000 the fourth most frequent cancer with 876 000 new cases (8.7% of the total) and 647 000 deaths (10.4% of all cancer deaths), The proportion of patients surviving 5 years after diagnosis remained nearly the same – about 20%. The new phenomenon is a changing frequency of malignant lesions, their increase in proximal part of the stomach which are caused by a more agressive diffuse, undifferentiated type of adenocarcinoma with worse prognosis. Decrease of intestinal type with lesions located in distal part of the stomach causes the reduction of gastric cancer as a whole. An important role for the future evolution and prevention of gastric cancer is the indication of Helicobacter pylori infection as carcinogenic to human beings.

Ročník 2003  Témy časopisu Gastroenterology for practice 4 / 2003

CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Rudolf Hyrdel, CSc.

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prof. MUDr. Juraj Bober, CSc.
MUDr. Ivan Bunganič
prof. MUDr. Petr Dítě, DrSc.
doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
MUDr. Juraj Májek, PhD.
prof. MUDr. Peter Mlkvý, CSc.
MUDr. Tomáš Šálek
MUDr. Renata Szépeová, PhD.
prof. MUDr. Anton Vavrečka, CSc.
MUDr. Mária Zakuciová

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Examples of citations:
1. Vaughan TL, Davis S, Kristal A, et al. Obesity, alcohol and tobacco risk factors for cancers of esophagus and gastric cardia :adenocarcinoma versus squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 1995; 4: 85-92.
2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
3. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.

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Origination of pigment stones is related to:
a. acute haemolysis
b. chronic haemolysis
c. hypercalcaemia
d. hyperlipoproteinaemia

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