Téma: 

Diagnosis and differential diagnosis of resistant peptcv ulcers

Rudolf Hyrdel

In spite of confirmed evidence of clinical importance of H. pylyori infection in the etiopathogenesis of peptic ulcers it still remains a polyetiologic syndrome and in the therapy of peptic ulcers not only skill in standard methods but also „medical arts“ are needed. Apart from H. pylori presence in etiopathogenesis of peptic ulcers also further factors disturbing gastric acid secretion and protective function of endogastric and duodenal mucosa are considered. Most of these disorders are genetically predisposed but also excessive stress, dietary and regime habits and use of various unhealthy substances play a role. More frequent ulcerogenetic drugs abuse is reported. Lesions similar to peptic ulcers can be induced by the range of diseases that have to be considered and carefully diagnosed. These diseses are usually „resistant“ to standard therapeutic methods. On basis of experience of diagnosis and therapy of more than 1 , 700 patients with resistant ulcers the authors described diagnostic and differential diagnostic methods.

Ročník 2004  Témy časopisu Gastroenterology for practice 3 / 2004

CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Rudolf Hyrdel, CSc.

MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Marian Bátovský, CSc., mim. prof. SZU
prof. MUDr. Juraj Bober, CSc.
MUDr. Ivan Bunganič
prof. MUDr. Petr Dítě, DrSc.
doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
MUDr. Juraj Májek, PhD.
prof. MUDr. Peter Mlkvý, CSc.
MUDr. Tomáš Šálek
MUDr. Renata Szépeová, PhD.
prof. MUDr. Anton Vavrečka, CSc.
MUDr. Mária Zakuciová

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Ing. Danica Paulenová
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SECTIONS

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The latest knowledge on disease and disease groups aetiology, pathogenesis, diagnoses and therapy.
Maximum size is 8 pages (font size 12, line spacing 1.5) with maximum five pictures (graphs). In case of more extensive theme elaboration it is possible to divide the paper to several parts after agreement with editorial office. Write the article with focus on its practical use for gastroenerologists and specialists from other disciplines interested in gastroenterology.

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Examples of citations:
1. Vaughan TL, Davis S, Kristal A, et al. Obesity, alcohol and tobacco risk factors for cancers of esophagus and gastric cardia :adenocarcinoma versus squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 1995; 4: 85-92.
2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
3. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.

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AUTODIDACTIC TEST

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Origination of pigment stones is related to:
a. acute haemolysis
b. chronic haemolysis
c. hypercalcaemia
d. hyperlipoproteinaemia

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