Téma:  Case Studies

Unusual case of advanced generalized sarcoidosis mimicking liver cirrhosis

Laura Gombošová, Peter Jarčuška, Peter Bohuš, Vladimír Sihotský, Mária Zakuciová, Ivica Lazúrová

Hepatic sarcoidosis represents an extrapulmonary manifestation of systemic granulomatous disease. Hepatic involvement is documented in 20 - 90 % patients, rarely granulomatous hepatitis is the sole manifestation of disease. Published rates underestimate the frequency of disorder, because many of cases are undiagnosed or misdiagnosed. Extent of organ involvement with progressive fibrosis determines the prognosis of disease. Authors present a case of hepatic sarcoidosis mimicking a liver cirrhosis with ascites. Hepatic sarcoidosis as the first extrapulmonary manifestation of the systemic sarcoidosis was diagnosed by complete examinations, including histology. Spleen, retroperitoneal lymph nodes and the peritoneum were also affected. The disease was manifested by unclear long-standing cholestatic hepatopathy with progressive fatigue and loss of weight.

Ročník 2007  Témy časopisu Gastroenterology for practice 3 / 2007

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MUDr. Ivan Bunganič
prof. MUDr. Petr Dítě, DrSc.
doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
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prof. MUDr. Peter Mlkvý, CSc.
MUDr. Tomáš Šálek
MUDr. Renata Szépeová, PhD.
prof. MUDr. Anton Vavrečka, CSc.
MUDr. Mária Zakuciová

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1. Vaughan TL, Davis S, Kristal A, et al. Obesity, alcohol and tobacco risk factors for cancers of esophagus and gastric cardia :adenocarcinoma versus squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 1995; 4: 85-92.
2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
3. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.

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Origination of pigment stones is related to:
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