Téma: 

Notes to pathogenesis of helicobacter pylori infection

Marian Bátovský

Helicobacter pylori infection continues to play a key role in gastric diseases. This infection has been accepted as the major cause of type B gastritis, which is strongly associated with duodenal ulcer and gastric ulcers disease. It is now 14 years since Helicobacter pylori was cited as a gastric carcinogen. In the latest available epidemiological studies, the presence of Helicobacter pylori infection combined with CagA antibody status increases risk of gastric cancer 20-fold compared with controls. One estimation attributed 70 % of distal gastric cancers to Helicobacter pylori. A number of studies show considerable variations in risk for gastric cancer development depending on Helicobacter pylori strain type and the genetic predisposition of the host. As yet, the precise sequence of molecular events leading to gastric cancer has not been elucidated.

Ročník 2008  Témy časopisu Gastroenterology for practice 1 / 2008

CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Rudolf Hyrdel, CSc.

MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Marian Bátovský, CSc., mim. prof. SZU
prof. MUDr. Juraj Bober, CSc.
MUDr. Ivan Bunganič
prof. MUDr. Petr Dítě, DrSc.
doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
MUDr. Juraj Májek, PhD.
prof. MUDr. Peter Mlkvý, CSc.
MUDr. Tomáš Šálek
MUDr. Renata Szépeová, PhD.
prof. MUDr. Anton Vavrečka, CSc.
MUDr. Mária Zakuciová

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Ing. Danica Paulenová
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Examples of citations:
1. Vaughan TL, Davis S, Kristal A, et al. Obesity, alcohol and tobacco risk factors for cancers of esophagus and gastric cardia :adenocarcinoma versus squamous cell carcinoma Cancer Epidemiol Biomarkers Prev 1995; 4: 85-92.
2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
3. Shaheen NJ, Crosby NA, Bozymski EM, et al. Is there publication bias in the reporting cancer risk in Barrett´ esophagus? Gastroenterology 2000; 119: 333-338.

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AUTODIDACTIC TEST

The editorial board reserves the right to make small stylistic changes in the paper. If it is necessary to shorten the paper, the consent of the author will be required. All articles are reviewed.

Origination of pigment stones is related to:
a. acute haemolysis
b. chronic haemolysis
c. hypercalcaemia
d. hyperlipoproteinaemia

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