Téma: 

Biological therapy of chronic non-specific bowel inflammations

Mária Zakuciová, Božena Nováková, Beáta Bodnárová, Laura Gombošová, Eduard Veselíny, Peter Jarčuška

Non-specific bowel inflammations are constant medical problem. Pathogenesis of the disease is not clear and thus therapy can partly affect some immunological processes. Therapy is complex, with biological therapy at the top, that removes abundant number of key cytokines. The subject of the presented work is the survey of anti TNF alpha substances which have been used for long in daily practice. At the end of the work our 5-year experience and results of treatment of patients with Crohn´s disease and ulcer disease are presented. We are pleased with improved clinical condition, endoscopic finding and better mental condition of patients; however, we have to be very careful in application of the therapy because of severe immunological impact on organism and possible complications.

Ročník 2008  Témy časopisu Gastroenterology for practice 2 / 2008

CHAIRMAN OF THE EDITORIAL BOARD
prof. MUDr. Rudolf Hyrdel, CSc.

MEMBERS OF THE EDITORIAL BOARD
doc. MUDr. Marian Bátovský, CSc., mim. prof. SZU
prof. MUDr. Juraj Bober, CSc.
MUDr. Ivan Bunganič
prof. MUDr. Petr Dítě, DrSc.
doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
MUDr. Juraj Májek, PhD.
prof. MUDr. Peter Mlkvý, CSc.
MUDr. Tomáš Šálek
MUDr. Renata Szépeová, PhD.
prof. MUDr. Anton Vavrečka, CSc.
MUDr. Mária Zakuciová

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Ing. Danica Paulenová
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Examples of citations:
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2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
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Origination of pigment stones is related to:
a. acute haemolysis
b. chronic haemolysis
c. hypercalcaemia
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