Peter Mlkvý, Peter Makovník, Juraj Májek, Anton Mateášik, Ivan Čavarga
Despite increasing incidence of esophageal adenocarcinoma within last decades an effective screening method has still been absent. Consequent endobioptic follow up of well known prekanceroses especially of Barrett´s esophagus represents practically the only alternative for detection of early cancer. Endoscopic therapy is indicated for high grade dysplastic and early cancer mucosal lesions (T1m). Conditio sine qua non for endoscopic treatment is precise staging including endobiopsy, CT and EUS. Unifocal elevated lesions are indicated for endoscopic mucosal resection, while flat and multifocal lesions are suitable for ablative therapy. Combination of therapeutic techniques seems to be optimal for certain type of lesions.