Ivan Ďuriš
Prevention of cancer in high gastric cancer risk groups is in accordance with experimental and epidemiological studies reasonable. Primary prevention of gastric cancer however is apart of healthcare system equally a problem of ecology, agriculture, and traffic as well. Physician can appeal only in secondary prevention in high risk groups (atrophic gastritis with intestinal metaplasia, gastric polyposis, xantelasmas, gastric remnant after B II resection 10-15 yrs. after operation, chronic H. pylori infection). Restriction of smoked food (3,4-benzpyren), broiled meat (pyrolysates of protein, tryptophayn, phenylalanin), salt, aflatoxin B (Aspergillus flavus in silage, nuts etc.) and high consume of fruit, vegetables (A, C and E vitamins) and selen are acting as chemopreventive agents.