Téma: 

Celiac disease as an autoimmune disease of the digestive tract

Ivana Stachová, Peter Bánovčin, Rudolf Hyrdel

Celiac disease as an autoimmune disease of the digestive tract is characterized by development of gluten intolerance that is in wheat, rye, barley and oat that results in enterocytes alteration and development of malabsorption syndrome. The disease can develop in predisposed individuals at any age, both sexes, prevalence is worldwide problem with slight geographic differences. Current estimated prevalence is 0.25-1 % involving clinical from of classic symptomatic, oligo or asymptomatic and latent forms of the disease. The golden standard in diagnostics is combination of serologic tests on presence of circulating autoantibodies and histological examination of the mucosa of the small intestine. Treatment is a long-life gluten-free dietary regime and substitution of missed nutrition elements. Prognosis of the disease is good in non-complicated and well treated cases, morbidity and mortality does not differ from whole population rates.

Ročník 2009  Témy časopisu Gastroenterology for practice 3 / 2009

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doc. MUDr. Martin Huorka, CSc.
doc. MUDr. Peter Makovník, CSc.
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prof. MUDr. Peter Mlkvý, CSc.
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2. Gao YT, McLaughlin JT, Gridley T, et al. Risk factors for esophageal cancer in Shanghai, China. Role of diet and nutrients. Int J Cancer 1994; 58: 197-202.
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Origination of pigment stones is related to:
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