Mária Szántová
Nowadays cirrhosis is the most frequent cause of gastrointestinal non-tumoral mortality in the Western countries. It is
a main risk factor (RF) of HCC, the incidence of which has increased in the last decades up to 3 times. The main risk factors
for cirrhosis, participating in up to ¾ of its origination are preventable (alcohol, metabolic RF, viruses of hepatitis B
and C). The paper analyses the possibilities of searching for these RF (persons at risk, way of searching, screening algorithm)
as well as subsequent preventive measures. Just the third question manages to identify unhealthy consumption
and to indicate performance of the whole AUDIT test. The screening method to detect risky drinking is AUDIT-C test.
The result in point will recommend preventive-therapeutical measures. In the screening NAFLD there are key metabolic
RF (BMI > 25, waist circumference > 94/80 cm, hypertension, glucose > 6.1 mmol/l, HDL < 1/1.3 mmol/l, TG > 1.7, ferritin
>350 ug/l). The most effective method of area screening NAFLD is FLI test and NAFLD score with higher sensitivity
in comparison with USG. HBsAg and anti HCV tests proved suitable for hepatitis screening. The detection of the stated
RF allows a quick preventive-therapeutical procedure.